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In he received his Bachelor of Arts degree in political science from the University of Idaho. At the University of Idaho, he was student body president and a member of the Delta Chi fraternity. Craig was a member of the Idaho Army National Guard from to , attaining the rank of Private First Class E3 , [12] after which he received an honorable discharge. House of Representatives, representing Idaho's 1st Congressional District.
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Development[ edit ] The genetic and epigenetic changes just described occur in a step-wise fashion. The initial change, often involving one of the cited chromosome 14 translocations, establishes a clone of bone marrow plasma cells that causes the asymptomatic disorder termed monoclonal gammopathy of undetermined significance MGUS. MGUS is a premalignant disorder characterized by increased numbers of plasma cells in the bone marrow or the circulation of a myeloma protein immunoglobulin. Further genetic or epigenic changes produce a new clone of bone marrow plasma cells, usually descendant from the original clone, that causes a more serious but still asymptomatic premalignant disorder termed smoldering multiple myeloma. Smoldering multiple myeloma is characterized by a rise in the number of bone marrow plasma cells or levels of the circulating myeloma protein above that seen in MGUS. Subsequent genetic and epigenetic changes lead to a new, more aggressive clone of plasma cells which cause further rises in the level of the circulating myeloma protein, further rises in the number of bone marrow plasma cells, or the development of one or more of a specific set of "CRAB" symptoms see diagnostic section below. These last changes are the basis for diagnosing malignant multiple myeloma and treating the disease.
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Burk We no longer feel the social pressure to confine sex to committed relationships. Sex is now an accepted recreational activity. We may have overcome our fear and shame about sex, but many of us still have issues regarding intimacy. If we experience more intimacy than we can handle, we will feel threatened; our safety checklist will be triggered. When we experience an orgasm, we reveal ourselves more completely and more honestly than at any other time.
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